Potassium accumulation in the globally ischemic mammalian heart. A role for the ATP-sensitive potassium channel.
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چکیده
منابع مشابه
Potassium accumulation in the globally ischemic mammalian heart. A role for the ATP-sensitive potassium channel.
We investigated the contribution of opening of the ATP-sensitive K+ channel to extracellular accumulation of K+ during ischemia with the use of glibenclamide, a specific blocker of this K+ channel. To characterize the electrophysiological effects of glibenclamide during metabolic inhibition (by either application of dinitrophenol or hypoxia) we performed patch-clamp studies in isolated membrane...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1990
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.67.4.835